277 SynNotch-CAR T cells demonstrate potent anti-tumor efficacy in a preclinical immunocompetent mouse model for glioblastoma

• Yuan Wang,
• Hideho Okada,
• Wendell Lim,
• Tiffany Chen,
• Takahide Nejo,
• Akane Yamamichi,
• Su Phyu,
• Senthilnath Lakshmanachetty,
• Payal Watchmaker,
• Milos Simic,
• Chanelle Shepherd,
• Jason Duecker,
• Olga Troyanskaya,
• Lia Cardarelli,
• Sachdev Sidhu

Affiliations

Yuan Wang

Thoracic Clinical College, Tianjin Medical University, Tianjin, Tianjin, China

Hideho Okada

1University of California, San Francisco, San Francisco, CA, USA

Wendell Lim

1University of California San Francisco, San Francisco, CA, USA

Tiffany Chen

1 Cardiovascular Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA

Takahide Nejo

1University of California San Francisco, San Francisco, CA, USA

Akane Yamamichi

Department of Neurology, UCSF, San Francisco, California, USA

Su Phyu

1University of California, San Francisco, San Francisco, CA, USA

Senthilnath Lakshmanachetty

1University of California, San Francisco, San Francisco, CA, USA

Payal Watchmaker

1University of California, San Francisco, San Francisco, CA, USA

Milos Simic

1University of California San Francisco, San Francisco, CA, USA

Chanelle Shepherd

1University of California San Francisco, San Francisco, CA, USA

Jason Duecker

1University of California San Francisco, San Francisco, CA, USA

Olga Troyanskaya

2Princeton University, Princeton, NJ, USA

Lia Cardarelli

3University of Toronto, Toronto, ON, Canada

Sachdev Sidhu

3University of Toronto, Toronto, ON, Canada