Engineered fluoride sensitivity enables biocontainment and selection of genetically-modified yeasts

Justin I. Yoo; Susanna Seppälä; Michelle A. OʼMalley

doi:10.1038/s41467-020-19271-1

Nature Communications (Oct 2020)

Engineered fluoride sensitivity enables biocontainment and selection of genetically-modified yeasts

Justin I. Yoo,
Susanna Seppälä,
Michelle A. OʼMalley

Affiliations

Justin I. Yoo: Department of Chemical Engineering, University of California Santa Barbara
Susanna Seppälä: Department of Chemical Engineering, University of California Santa Barbara
Michelle A. OʼMalley: Department of Chemical Engineering, University of California Santa Barbara

DOI: https://doi.org/10.1038/s41467-020-19271-1
Journal volume & issue: Vol. 11, no. 1
pp. 1 – 9

Abstract

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Non-antibiotic selection systems could also serve as biocontainment strategies. Here the authors present a fluoride sensitivity selection system for use in yeast.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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