Communications Chemistry (Oct 2021)

Two-photon activated precision molecular photosensitizer targeting mitochondria

  • Inês F. A. Mariz,
  • Sandra N. Pinto,
  • Ana M. Santiago,
  • José M. G. Martinho,
  • Javier Recio,
  • Juan J. Vaquero,
  • Ana M. Cuadro,
  • Ermelinda Maçôas

DOI
https://doi.org/10.1038/s42004-021-00581-4
Journal volume & issue
Vol. 4, no. 1
pp. 1 – 11

Abstract

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Molecules that target mitochondria have promising applications as anticancer agents. Here quinolizinium and benzimidazolium cations are shown to deactivate mitochondria through two-photon absorption in the near infrared range.