Tra1 controls the transcriptional landscape of the aging cell

Khaleda Afrin Bari; Matthew D Berg; Julie Genereaux; Christopher J Brandl; Patrick Lajoie

doi:10.1093/g3journal/jkac287

G3: Genes, Genomes, Genetics (Oct 2022)

Tra1 controls the transcriptional landscape of the aging cell

Khaleda Afrin Bari,
Matthew D Berg,
Julie Genereaux,
Christopher J Brandl,
Patrick Lajoie

Affiliations

Khaleda Afrin Bari: ORCiD; Department of Anatomy and Cell Biology, The University of Western Ontario, London, ON N6A 5C1, Canada
Matthew D Berg: ORCiD; Department of Biochemistry, The University of Western Ontario, London, ON N6A 5C1, Canada
Julie Genereaux: Department of Anatomy and Cell Biology, The University of Western Ontario, London, ON N6A 5C1, Canada
Christopher J Brandl: ORCiD; Department of Biochemistry, The University of Western Ontario, London, ON N6A 5C1, Canada
Patrick Lajoie: ORCiD; Department of Anatomy and Cell Biology, The University of Western Ontario, London, ON N6A 5C1, Canada

DOI: https://doi.org/10.1093/g3journal/jkac287
Journal volume & issue: Vol. 13, no. 1

Abstract

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AbstractGene expression undergoes considerable changes during the aging process. The mechanisms regulating the transcriptional response to cellular aging remain poorly understood. Here, we employ the budding yeast Saccharomyces cerevisiaeTRA1tra1Q3tra1Q3CTA1CTT1tra1Q3tra1Q3stra1Q3s

Published in G3: Genes, Genomes, Genetics

ISSN: 2160-1836 (Online)
Publisher: Oxford University Press
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General): Genetics
Website: https://academic.oup.com/g3journal

About the journal