THE FUNCTION OF HYPOPHYSIS-THYROID SYSTEM IN PATIENTS WITH ALCOHOLISM DEPENDING ON IODINE SUFFICIENCY OF THE HUMAN BODY

Abstract

The aim of our investigation was to study the hypophysis- thyroid status of a body in patients with alcoholism, the inhabitants of various biogeochemical zones of the Transcarpathia, in the highlands – with expressed iodine deficiency and in the lowlands – with lower degree of iodine insufficiency. The content of thyroxin, triiodothyromine, thyrotropic hormone in blood serum has been defined by radioimmunologic method with the use of standard test- sets. The general iodine in the blood and urine has been studied by cerium-arsenide method. The peculiarities as to the influence of various ecologically iodine supply of the body upon TSH function of the hypophysis, hormone function of the thyroid gland, iodine reserves of the body both in practically healthy people and in alcoholism have been established. Alcoholism has been shown to be accompanied by the increased losses of iodine with urine and the depletion of the iodine reserves of the body, the increase of T3 level in blood serum both in lowlands and highlands of the Transcarpathia, it being characterized by different degrees of iodine deficiency complicating the existing iodine deficiency of the body. These findings may be good reasons for including iodine correction into the treatment of alcoholism.

Keywords

• hypophysis-thyroid system
• alcoholism
• iodine-conditioned sufficiency
• hormone