Incidental testicular germ cell tumor in a transgender woman: A case report

Abstract

Testicular cancer found incidentally during gender-affirming orchiectomy is infrequently reported in the literature. This report details a 27-year-old transgender woman whose testicular cancer was discovered incidentally upon routine histopathologic examination of the orchiectomy specimen. The patient did not present with any clinical signs of malignancy. There was no evidence of metastases after further workup and the patient was able to resume hormone therapy after surgery. Transgender individuals must be screened according to their natal anatomy and even in absence of clinical signs excised tissue should be examined for possible malignancy.

Keywords

• Gender-affirming orchiectomy
• Testicular cancer
• Germ cell tumor
• Asymptomatic malignancy