Nature Communications (May 2017)
Evolutionary dynamics and genomic features of the Elizabethkingia anophelis 2015 to 2016 Wisconsin outbreak strain
- Amandine Perrin,
- Elise Larsonneur,
- Ainsley C. Nicholson,
- David J. Edwards,
- Kristin M. Gundlach,
- Anne M. Whitney,
- Christopher A. Gulvik,
- Melissa E. Bell,
- Olaya Rendueles,
- Jean Cury,
- Perrine Hugon,
- Dominique Clermont,
- Vincent Enouf,
- Vladimir Loparev,
- Phalasy Juieng,
- Timothy Monson,
- David Warshauer,
- Lina I. Elbadawi,
- Maroya Spalding Walters,
- Matthew B. Crist,
- Judith Noble-Wang,
- Gwen Borlaug,
- Eduardo P. C. Rocha,
- Alexis Criscuolo,
- Marie Touchon,
- Jeffrey P. Davis,
- Kathryn E. Holt,
- John R. McQuiston,
- Sylvain Brisse
Affiliations
- Amandine Perrin
- Institut Pasteur, Microbial Evolutionary Genomics
- Elise Larsonneur
- Institut Pasteur, Microbial Evolutionary Genomics
- Ainsley C. Nicholson
- Division of High Consequence Pathogens and Pathology, Special Bacteriology Reference Laboratory, Bacterial Special Pathogens Branch, Centers for Disease Control and Prevention
- David J. Edwards
- Centre for Systems Genomics, University of Melbourne
- Kristin M. Gundlach
- Wisconsin State Laboratory of Hygiene
- Anne M. Whitney
- Division of High Consequence Pathogens and Pathology, Special Bacteriology Reference Laboratory, Bacterial Special Pathogens Branch, Centers for Disease Control and Prevention
- Christopher A. Gulvik
- Division of High Consequence Pathogens and Pathology, Special Bacteriology Reference Laboratory, Bacterial Special Pathogens Branch, Centers for Disease Control and Prevention
- Melissa E. Bell
- Division of High Consequence Pathogens and Pathology, Special Bacteriology Reference Laboratory, Bacterial Special Pathogens Branch, Centers for Disease Control and Prevention
- Olaya Rendueles
- Institut Pasteur, Microbial Evolutionary Genomics
- Jean Cury
- Institut Pasteur, Microbial Evolutionary Genomics
- Perrine Hugon
- Institut Pasteur, Microbial Evolutionary Genomics
- Dominique Clermont
- CIP—Collection de l'Institut Pasteur, Institut Pasteur
- Vincent Enouf
- Institut Pasteur, Pasteur International Bioresources network (PIBnet), Plateforme de Microbiologie Mutualisée (P2M)
- Vladimir Loparev
- Division of Scientific Resources, Centers for Disease Control and Prevention
- Phalasy Juieng
- Division of Scientific Resources, Centers for Disease Control and Prevention
- Timothy Monson
- Wisconsin State Laboratory of Hygiene
- David Warshauer
- Wisconsin State Laboratory of Hygiene
- Lina I. Elbadawi
- Epidemic Intelligence Service, Centers for Disease Control and Prevention
- Maroya Spalding Walters
- Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention
- Matthew B. Crist
- Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention
- Judith Noble-Wang
- Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention
- Gwen Borlaug
- Division of Public Health, Wisconsin Department of Health Services
- Eduardo P. C. Rocha
- Institut Pasteur, Microbial Evolutionary Genomics
- Alexis Criscuolo
- Institut Pasteur, Hub Bioinformatique et Biostatistique, C3BI, USR 3756 IP CNRS
- Marie Touchon
- Institut Pasteur, Microbial Evolutionary Genomics
- Jeffrey P. Davis
- Division of Public Health, Wisconsin Department of Health Services
- Kathryn E. Holt
- Centre for Systems Genomics, University of Melbourne
- John R. McQuiston
- Division of High Consequence Pathogens and Pathology, Special Bacteriology Reference Laboratory, Bacterial Special Pathogens Branch, Centers for Disease Control and Prevention
- Sylvain Brisse
- Institut Pasteur, Microbial Evolutionary Genomics
- DOI
- https://doi.org/10.1038/ncomms15483
- Journal volume & issue
-
Vol. 8,
no. 1
pp. 1 – 12
Abstract
Elizabethkingia anophelis is an emerging pathogen of high antimicrobial resistance. Perrin and colleagues sequenced isolates of a 2015/2016 E. anophelis outbreak in Wisconsin and found substantial genetic diversity, accelerated evolutionary rate and a disruptive mutation in the DNA repair gene mutY.
