A case of primary clear cell hepatocellular carcinoma comprised mostly of clear cells

Reiji Kokubo, MD; Kazuhiro Saito, MD, phD; Natsuhiko Shirota, MD, phD; Yukari Wakabayashi, MD, phD; Akihiko Tsuchida, MD, phD; Takeshi Nagai, MD, phD; Toshitaka Nagao, MD, phD

Radiology Case Reports (Nov 2019)

A case of primary clear cell hepatocellular carcinoma comprised mostly of clear cells

Reiji Kokubo, MD,
Kazuhiro Saito, MD, phD,
Natsuhiko Shirota, MD, phD,
Yukari Wakabayashi, MD, phD,
Akihiko Tsuchida, MD, phD,
Takeshi Nagai, MD, phD,
Toshitaka Nagao, MD, phD

Affiliations

Reiji Kokubo, MD: Department of Radiology, Tokyo Medical University, 6-7-1 Nishi-shinjuku, Shinjuku-ku, Tokyo 160-0023, Japan; Corresponding author.
Kazuhiro Saito, MD, phD: Department of Radiology, Tokyo Medical University, 6-7-1 Nishi-shinjuku, Shinjuku-ku, Tokyo 160-0023, Japan
Natsuhiko Shirota, MD, phD: Department of Radiology, Tokyo Medical University, 6-7-1 Nishi-shinjuku, Shinjuku-ku, Tokyo 160-0023, Japan
Yukari Wakabayashi, MD, phD: Department of Radiology, Kohsei Chuo General Hospital, 1-11-7 Mita, Meguro-ku, Tokyo 153-0062, Japan
Akihiko Tsuchida, MD, phD: Department of Gastrointestinal and Pediatric Surgery, Tokyo Medical University, 6-7-1 Nishi-shinjuku, Shinjuku-ku, Tokyo 160-0023, Japan
Takeshi Nagai, MD, phD: Department of Anatomic Pathology, Tokyo Medical University, 6-7-1 Nishi-shinjuku, Shinjuku-ku, Tokyo 160-0023, Japan
Toshitaka Nagao, MD, phD: Department of Anatomic Pathology, Tokyo Medical University, 6-7-1 Nishi-shinjuku, Shinjuku-ku, Tokyo 160-0023, Japan

Journal volume & issue: Vol. 14, no. 11
pp. 1377 – 1381

Abstract

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Clear cell hepatocellular carcinoma (CHCC) is defined as a tumor which contains more than 50% of clear cells. However, CHCC with more than 90% of clear cells are extremely rare. We report a case of a 65-year-old woman who was found to have a solitary mass, which was histologically diagnosed as clear cell hepatocellular carcinoma composed of 90% or more clear cells. The tumor presented rim arterial phase hyperenhancement in computed tomography, magnetic resonance imaging, and computed tomography during hepatic arteriography, and was classified as LR-M category according to The Liver Imaging Reporting and Data System version 2018(LI-RADS v2018). This tumor may mimic other tumors with similar radiographic features, such as intrahepatic cholangiocellular carcinoma and metastatic tumor. Keywords: Clear cell hepatocellular carcinoma, Hepatocellular carcinoma, Clear cell carcinoma, Computed tomography, Magnetic resonance imaging

Published in Radiology Case Reports

ISSN: 1930-0433 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: https://www.sciencedirect.com/journal/radiology-case-reports

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