Nature Communications (Nov 2018)

Structural basis for the second step of group II intron splicing

  • Russell T. Chan,
  • Jessica K. Peters,
  • Aaron R. Robart,
  • Timothy Wiryaman,
  • Kanagalaghatta R. Rajashankar,
  • Navtej Toor

DOI
https://doi.org/10.1038/s41467-018-06678-0
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 10

Abstract

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Group II introns are large, self-splicing RNAs that catalyze their own excision from pre-mRNA molecules. Here the authors determine the 3.7 Å crystal structure of the group II intron in the stage immediately before the second step of splicing and present a complete model for the second step of group II intron splicing.