Antibiotic Resistance of Urinary Tract Infection of Children Under 14 Years Admitted To The Pediatric Clinic of Imam Sajjad Hospital, 2012

Abstract

Background & aim: Urinary tract infection is the most common childhood infections after upper respiratory tract infection. Early diagnosis, proper treatment and appropriate patient follow-up can lead to a significant reduction in symptoms. The purpose of this study was to determine the antimicrobial resistance of urinary tract infection in children under 14 years admitted to the pediatric clinic of Imam Sajjad (AS) Yasooj. Methods: Methods: In this cross-sectional study antibiotic sensitivity of 145 positive urine cultures were evaluated by disc diffusion method. Urine specimens were collected by suprapubic aspiration and catheterization urethral in children without urinary incontinence and Mid Stream Clean-Catch method. Data were analyzed by chi square test. Results: Among the patients were studied, 60.68% female and 39.31% were male. The most common cause of urinary tract infections in children, Escherichia coli (72.41%), followed by Klebsiella (34/10.34%). Antibiotic resistance patterns including ampicillin (85.51%), amoxicillin (/83.44%), cephalexin (69.65%), cephalothin (62.06%), cotrimoxazole (37.61%), nalidixic acid (44.82%), cefixime (24.37%), nitrofurantoin (36.55%), gentamicin (35.17%), ceftriaxone (28.27%), ciprofloxacin (26.89%), amikacin (25.51%), and cefotaxime (24.82%) were respectively. Conclusion: Conclusion: Antibiotic resistance in urinary tract infections of children in Yasuj in 2012 was higher than previous years except for amikacin, But it was a remarkable increase in ciprofloxacin and co-trimoxazole. The use of nitrofurantoin, cefotaxime, third generation cephalosporins and aminoglycosides is recommended for empirical treatment.

Keywords

• UTI
• Children
• Antibiotic Resistance
• Antibiogram