Analysis of the bacterial vaginosis predictive significance in the diagnosis of inflammatory processes in female pelvic minor

Abstract

Pelvic inflammatory disease (PID) has an incidence of 100-200/100,000. The aim of this study was to determine whether there is a correlation between the serum proinflammatory cytokines IL-1β and IFN-γ and the presence of bacterial vaginosis (BV) or chlamydia infections (Chl) in women with symptoms of inflammatory processes in the pelvic minor. The study included fifty patients diagnosed with PID and an average age of 32 years. The results of this study revealed that the number of women with BV and PID presented increased IL-1β levels in the serum, whereas in women with chlamydial infections and PID serum the level of IFN-γ was increased. The study shows that in patients with PID, in whom there was no diagnosis of BV and infection with Chlamydia trachomatis, the levels of IL-1β and IFN-γ were increased. The conclusion of this research points to the importance of monitoring levels of cytokines in patients with homeostasis of vaginal flora disorders in the prevention of PID.

Keywords

• Bacterial vaginosis
• Chlamydia trachomatis
• interleukins
• pelvic minor infection