BMC Biology (Dec 2023)

Leveraging the predictive power of 3D organoids in dogs to develop new treatments for man and man’s best friend

  • Karin Allenspach,
  • Yana Zavros,
  • Mohamed Elbadawy,
  • Christopher Zdyrski,
  • Jonathan Paul Mochel

DOI
https://doi.org/10.1186/s12915-023-01799-5
Journal volume & issue
Vol. 21, no. 1
pp. 1 – 5

Abstract

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Recent progress in adult stem cell technology, along with interdisciplinary collaboration in the field of One Health, has accelerated the development of 3D organoid cultures in non-model animals, such as dogs. These advancements have the potential to significantly impact disease modeling and drug development for many diseases shared between man and man’s best friend.