International Journal of Molecular Sciences (Oct 2014)

Platelets: Still a Therapeutical Target for Haemostatic Disorders

  • Reinaldo Barros Geraldo,
  • Plínio Cunha Sathler,
  • André Luiz Lourenço,
  • Max Seidy Saito,
  • Lucio M. Cabral,
  • Pabulo Henrique Rampelotto,
  • Helena Carla Castro

DOI
https://doi.org/10.3390/ijms151017901
Journal volume & issue
Vol. 15, no. 10
pp. 17901 – 17919

Abstract

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Platelets are cytoplasmatic fragments from bone marrow megakaryocytes present in blood. In this work, we review the basis of platelet mechanisms, their participation in syndromes and in arterial thrombosis, and their potential as a target for designing new antithrombotic agents. The option of new biotechnological sources is also explored.

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