Changing the phenotypes − Epigenetics in ayurveda

Abstract

Objective: The primary objective is to elaborate the various concepts concerning genetics and epigenetics in Ayurveda. Data Source: The classical Ayurveda texts, along with the commentaries and peer-reviewed articles, were referred. The classical information was further analyzed and concluded. Review Method: Systematic review after studying changes in phenotypes with a view-through epigenetics will be a scientific contribution to generate interest among medical fraternity for better public health contribution. Results: The four major factors influencing the phenotypes are lifestyle and behavior, diet and digestion, stress and the environment we live in. It is not only genes that are the cause of numerous disorders our children are facing but, also the surrounding (both living and nonliving) that lays an impact, thus changing the “gene expression,” thus changing a whole lot of traits. Conclusions: Genes are affected by several factors and processes including development in utero and childhood, environmental chemicals, drugs, and pharmaceuticals, aging, and diet thus inducing epigenetic changes through developmental plasticity which may land up into diseases with transgenerational inheritance. This comprehension will lead to better integration with the current medical system in managing optimal health of the public sector.

Keywords

• gene expression
• gene
• phenotype
• prakriti