Molecules (Jan 2021)

Lactoferrin: A Glycoprotein Involved in Immunomodulation, Anticancer, and Antimicrobial Processes

  • Quintín Rascón-Cruz,
  • Edward A. Espinoza-Sánchez,
  • Tania S. Siqueiros-Cendón,
  • Sayuri I. Nakamura-Bencomo,
  • Sigifredo Arévalo-Gallegos,
  • Blanca F. Iglesias-Figueroa

DOI
https://doi.org/10.3390/molecules26010205
Journal volume & issue
Vol. 26, no. 1
p. 205

Abstract

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Lactoferrin is an iron binding glycoprotein with multiple roles in the body. Its participation in apoptotic processes in cancer cells, its ability to modulate various reactions of the immune system, and its activity against a broad spectrum of pathogenic microorganisms, including respiratory viruses, have made it a protein of broad interest in pharmaceutical and food research and industry. In this review, we have focused on describing the most important functions of lactoferrin and the possible mechanisms of action that lead to its function.

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