A magnetic antibody-conjugated nano-system for selective delivery of Ca(OH)2 and taxotere in ovarian cancer cells

Reza Taheri-Ledari; Ehsan Zolfaghari; Simindokht Zarei-Shokat; Amir Kashtiaray; Ali Maleki

doi:10.1038/s42003-022-03966-w

Communications Biology (Sep 2022)

A magnetic antibody-conjugated nano-system for selective delivery of Ca(OH)2 and taxotere in ovarian cancer cells

Reza Taheri-Ledari,
Ehsan Zolfaghari,
Simindokht Zarei-Shokat,
Amir Kashtiaray,
Ali Maleki

Affiliations

Reza Taheri-Ledari: Catalysts and Organic Synthesis Research Laboratory, Department of Chemistry, Iran University of Science and Technology
Ehsan Zolfaghari: Catalysts and Organic Synthesis Research Laboratory, Department of Chemistry, Iran University of Science and Technology
Simindokht Zarei-Shokat: Catalysts and Organic Synthesis Research Laboratory, Department of Chemistry, Iran University of Science and Technology
Amir Kashtiaray: Catalysts and Organic Synthesis Research Laboratory, Department of Chemistry, Iran University of Science and Technology
Ali Maleki: Catalysts and Organic Synthesis Research Laboratory, Department of Chemistry, Iran University of Science and Technology

DOI: https://doi.org/10.1038/s42003-022-03966-w
Journal volume & issue: Vol. 5, no. 1
pp. 1 – 16

Abstract

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A magnetic drug delivery system containing polyvinyl alcohol, gold nanoparticles, and sortilin antibody followed by the plasmonic photothermal heating strategy for the controlled drug release is proposed, with use in ovarian cancer demonstrated.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

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