A supramolecular photosensitizer derived from an Arene-Ru(II) complex self-assembly for NIR activated photodynamic and photothermal therapy

Gang Xu; Chengwei Li; Chen Chi; Luyan Wu; Yanyan Sun; Jian Zhao; Xing-Hua Xia; Shaohua Gou

doi:10.1038/s41467-022-30721-w

Nature Communications (Jun 2022)

A supramolecular photosensitizer derived from an Arene-Ru(II) complex self-assembly for NIR activated photodynamic and photothermal therapy

Gang Xu,
Chengwei Li,
Chen Chi,
Luyan Wu,
Yanyan Sun,
Jian Zhao,
Xing-Hua Xia,
Shaohua Gou

Affiliations

Gang Xu: Jiangsu Province Hi-Tech Key Laboratory for Biomedical Research and Pharmaceutical Research Center, School of Chemistry and Chemical Engineering, Southeast University
Chengwei Li: Jiangsu Province Hi-Tech Key Laboratory for Biomedical Research and Pharmaceutical Research Center, School of Chemistry and Chemical Engineering, Southeast University
Chen Chi: State Key Lab of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University
Luyan Wu: State Key Lab of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University
Yanyan Sun: School of Chemistry and Life Sciences, Suzhou University of Science and Technology
Jian Zhao: Jiangsu Province Hi-Tech Key Laboratory for Biomedical Research and Pharmaceutical Research Center, School of Chemistry and Chemical Engineering, Southeast University
Xing-Hua Xia: State Key Lab of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University
Shaohua Gou: Jiangsu Province Hi-Tech Key Laboratory for Biomedical Research and Pharmaceutical Research Center, School of Chemistry and Chemical Engineering, Southeast University

DOI: https://doi.org/10.1038/s41467-022-30721-w
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 14

Abstract

Read online

Photosensitisers are used in phototherapy to kill cancer cells. Here, the authors describe an organometallic Ru(II)-arene that functions as a phtotosensitiser and produces singlet oxygen and tumour regression in mice

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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