Determination of L-Ascorbic Acid Using MBs-AOX/GO/IGZO/Al by Wireless Sensing System and Microfluidic Framework

Jung-Chuan Chou; You-Xiang Wu; Po-Yu Kuo; Chih-Hsien Lai; Yu-Hsun Nien; Si-Hong Lin; Siao-Jie Yan; Cian-Yi Wu

doi:10.1109/ACCESS.2019.2907964

IEEE Access (Jan 2019)

Determination of L-Ascorbic Acid Using MBs-AOX/GO/IGZO/Al by Wireless Sensing System and Microfluidic Framework

Jung-Chuan Chou,
You-Xiang Wu,
Po-Yu Kuo,
Chih-Hsien Lai,
Yu-Hsun Nien,
Si-Hong Lin,
Siao-Jie Yan,
Cian-Yi Wu

Affiliations

Jung-Chuan Chou: ORCiD; Graduate School of Electronic Engineering, National Yunlin University of Science and Technology, Douliou, Taiwan
You-Xiang Wu: Graduate School of Electronic Engineering, National Yunlin University of Science and Technology, Douliou, Taiwan
Po-Yu Kuo: Graduate School of Electronic Engineering, National Yunlin University of Science and Technology, Douliou, Taiwan
Chih-Hsien Lai: Graduate School of Electronic Engineering, National Yunlin University of Science and Technology, Douliou, Taiwan
Yu-Hsun Nien: Graduate School of Chemical and Materials Engineering, National Yunlin University of Science and Technology, Douliou, Taiwan
Si-Hong Lin: Graduate School of Electronic Engineering, National Yunlin University of Science and Technology, Douliou, Taiwan
Siao-Jie Yan: Graduate School of Electronic Engineering, National Yunlin University of Science and Technology, Douliou, Taiwan
Cian-Yi Wu: Graduate School of Electronic Engineering, National Yunlin University of Science and Technology, Douliou, Taiwan

DOI: https://doi.org/10.1109/ACCESS.2019.2907964
Journal volume & issue: Vol. 7
pp. 45872 – 45880

Abstract

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In this paper, the L-ascorbic acid (L-AA) biosensor based on magnetic beads-ascorbate oxidase/graphene oxide/indium gallium zinc oxide/aluminum (MBs-AOX/GO/IGZO/Al) membrane was integrated with the potentiometric measurement system with the microfluidic framework in order to investigate the different sensing characteristics under the static condition and the dynamic condition. The L-AA biosensor showed the average sensitivity of 78.9 mV/decade (25 °C) under the static condition, and it showed the average sensitivity of 81.7 mV/decade (25 °C) at the optimal flow rate (25 μl/min). Besides, the XBee module was used to apply in the remote detection for the L-AA biosensor, and the experimental results were shown the average sensitivity of 78.7 mV/decade (25 °C). Moreover, we also investigated various experiments, such as temperature effect, hysteresis effect, and lifetime. These experimental results would be beneficial to the development of the L-AA biosensor based on electrochemical detection.

Published in IEEE Access

ISSN: 2169-3536 (Online)
Publisher: IEEE
Country of publisher: United States
LCC subjects: Technology: Electrical engineering. Electronics. Nuclear engineering
Website: https://ieeexplore.ieee.org/xpl/RecentIssue.jsp?punumber=6287639

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