Romanian Journal of Laboratory Medicine (Jan 2020)

Gastric cancer is associated with a high rate of microsatellite instability versus chronic gastritis: A retrospective study

  • Xing Li,
  • Guo Hua,
  • Zheng Dongjie,
  • Liu Jin,
  • Zhou Baojun,
  • Li Yanping,
  • Wang Ning,
  • Zhao Pu,
  • Liang Yan,
  • Wu Wenxin,
  • Li Guixin

DOI
https://doi.org/10.2478/rrlm-2020-0006
Journal volume & issue
Vol. 28, no. 1
pp. 57 – 65

Abstract

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Objective: Microsatellite instability (MSI) in gastric cancer contributes to genetic complexities of gastric cancer. In the current study, we employed a panel of mononucleotide and dinucleotide markers to detect MSI in 99 gastric cancer patients and 91 chronic gastritis patients and further analyzed the association of MSI with clinicopathologic variables of the study patients.

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