Extracorporeal Membrane Oxygenation (ECMO)-Associated Coagulopathy in Adults

Frantzeska Frantzeskaki; Dimitrios Konstantonis; Michail Rizos; Vasileios Kitsinelis; Georgios Skyllas; Ioannis Renieris; Maria Doumani; Vasileios Kolias; Eirini Kefalidi; Dimitrios Angouras; Argyrios Tsantes; Iraklis Tsangaris

doi:10.3390/diagnostics13233496

Diagnostics (Nov 2023)

Extracorporeal Membrane Oxygenation (ECMO)-Associated Coagulopathy in Adults

Frantzeska Frantzeskaki,
Dimitrios Konstantonis,
Michail Rizos,
Vasileios Kitsinelis,
Georgios Skyllas,
Ioannis Renieris,
Maria Doumani,
Vasileios Kolias,
Eirini Kefalidi,
Dimitrios Angouras,
Argyrios Tsantes,
Iraklis Tsangaris

Affiliations

Frantzeska Frantzeskaki: 2nd Critical Care Department, Attikon University Hospital, Medical School, National and Kapodistrian University of Athens, 157 72 Athens, Greece
Dimitrios Konstantonis: 2nd Critical Care Department, Attikon University Hospital, Medical School, National and Kapodistrian University of Athens, 157 72 Athens, Greece
Michail Rizos: 2nd Critical Care Department, Attikon University Hospital, Medical School, National and Kapodistrian University of Athens, 157 72 Athens, Greece
Vasileios Kitsinelis: 2nd Critical Care Department, Attikon University Hospital, Medical School, National and Kapodistrian University of Athens, 157 72 Athens, Greece
Georgios Skyllas: 2nd Critical Care Department, Attikon University Hospital, Medical School, National and Kapodistrian University of Athens, 157 72 Athens, Greece
Ioannis Renieris: 2nd Critical Care Department, Attikon University Hospital, Medical School, National and Kapodistrian University of Athens, 157 72 Athens, Greece
Maria Doumani: 2nd Critical Care Department, Attikon University Hospital, Medical School, National and Kapodistrian University of Athens, 157 72 Athens, Greece
Vasileios Kolias: Department of Cardiac Surgery, Attikon University Hospital, Medical School, National and Kapodistrian University of Athens, 157 72 Athens, Greece
Eirini Kefalidi: Department of Cardiac Surgery, Attikon University Hospital, Medical School, National and Kapodistrian University of Athens, 157 72 Athens, Greece
Dimitrios Angouras: Department of Cardiac Surgery, Attikon University Hospital, Medical School, National and Kapodistrian University of Athens, 157 72 Athens, Greece
Argyrios Tsantes: Laboratory of Haematology, Blood Bank Unit, Attikon University Hospital, Medical School, National and Kapodistrian University of Athens, 157 72 Athens, Greece
Iraklis Tsangaris: 2nd Critical Care Department, Attikon University Hospital, Medical School, National and Kapodistrian University of Athens, 157 72 Athens, Greece

DOI: https://doi.org/10.3390/diagnostics13233496
Journal volume & issue: Vol. 13, no. 23
p. 3496

Abstract

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Extracorporeal membrane oxygenation (ECMO) is used for the management of severe respiratory and cardiac failure and as a bridge to achieve definite treatment or transplantation. ECMO-associated coagulopathy (EAC) is a frequent complication leading to high rates of thrombosis or severe haemorrhage, contributing to morbidity and mortality among patients. Understanding the pathophysiology of EAC is substantial for effectively managing patients on ECMO. We analyse the underlying mechanism of EAC and discuss the monitoring of the coagulation profile, combining the viscoelastic point-of-care assays with the conventional coagulation laboratory tests.

Published in Diagnostics

ISSN: 2075-4418 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Medicine: Medicine (General)
Website: http://www.mdpi.com/journal/diagnostics

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