Clinical and Biomedical Research (May 2022)

Central nervous system high-grade neuroepithelial tumor with BCOR alteration: case report

  • Marco Antonio Delazeri,
  • Maria Eduarda Kegler,
  • Rodrigo Alberton Da Silva,
  • Julia Belato Teixeira,
  • Matheus Henrique Benin Lima,
  • Orly Matheus Gampert Spannenberg,
  • Pablo Santiago,
  • Marcelo Ughini Crusius

Journal volume & issue
Vol. 42, no. 1

Abstract

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Central nervous system high-grade neuroepithelial tumors with BCOR alteration are a rare disease. Currently, there are only 24 cases reported in the literature. They are characterized by a change involving the BCOR gene and have a poor prognosis. Studies are needed to improve the current therapy and outcomes of these neoplasms. This case report describes the clinical history of a patient with this pathology and aims to contribute to the current knowledge about this new entity.