Chemotaxonomic and Pharmacological properties on Dendrobium chrysanthum Lindl.

Abstract

[Abstract]: Many species of Dendrobium have been commonly used in traditional Chinese medicine. The aim of this study was to provide a critical and comprehensive evaluation of the phytochemistry and pharmacological properties of Dendrobium chrysanthum Lindl., with the hope to provide meaningful guidelines for future investigations. In our study, 105 compounds were tentatively identified by UPLC/Q-TOF-MS/MS comprehensively, novel polyphenylpropanoids were detected and characterized from the genus Dendrobium. 63 compounds were obtained by repeatedly chromatographs and recrystallization. Among them, 27 compounds were firstly reported from the species D. chrysanthum. Some valuable compounds like pseudo-spirostanols and novel polyphenylpropanoids were found and identified in D. chrysanthum for the first time, which might constitute the key characteristics and chemotaxonomic significance that distinguish D. chrysanthum from other Dendrobium species. The pharmacological activities of D. chrysanthum were summarized including the anti-inflammatory, antioxidant, anti-tumor and hypoglycemic activities of the extract and purified constituents.

Keywords

• phytochemistry
• pharmacological properties
• chemotaxonomy
• Dendrobium chrysanthum Lindl