Are patients with COPD with emphysema more incompatible with home-use non-invasive mechanical ventilation?

Abstract

INTRODUCTION[|]Domiciliary non-invasive mechanical ventilation (NIMV) devices are increasingly used in patients with chronic obstructive pulmonary disease (COPD) related chronic respiratory failure (CRF). In this study, device compliance of COPD patients with and without emphysema was assessed.[¤]METHODS[|]In an observational cross-sectional study, 2014-2018, who applied to respiratory intensive care unit (ICU) outpatient clinic using domiciliary NIMV with chronic respiratory failure diagnosis patients with COPD who had a thorax CT within the past year were taken into the study. Demographic information, comorbidities, NIMV mode and duration of use, respiratory function test, arterial blood gas, whole blood count, C-reactive protein (CRP) and complications were recorded from outpatient clinic records. Both groups were compared in terms of the parameters examined.[¤]RESULTS[|]Forty patients (M, 75%) with a median age of 66 were included in the study. There was no difference between the groups in terms of NIMV compliance and NIMV pressures in the study. In the emphysema group, active smoking was statistically higher (p=0.026) and FEV1, FEV1/FVC and PEF25-75 were found to be lower. The comorbidities of both groups were similar and as a complication redness of the skin due to mask pressure was found in a patient in the emphysema group. There was no difference between groups in terms of arterial blood gas and inflammatory markers.[¤]DISCUSSION AND CONCLUSION[|]Because of the clinical benefit for patients, using of the NIMV is one of the ideal hours for home use. COPD subtypes do not make a difference on NIMV compliance. [¤]

Keywords

• chronic obstructive pulmonary disease
• emphysema
• chronic respiratory failure
• noninvasive mechanical ventilation
• patient compliance