A case of prosthetic joint infection due to opportunist yeast, Cyberlindnera fabianii

Abstract

Background and Purpose: Invasive fungal infections caused by Cyberlindnera fabianii have recently increased despite its low virulence potential. Limited information in widely used commercial biochemical identification systems, leads to underestimation of Cy. fabianii infections in the clinical setting.Case report: We report a case of prosthetic joint infection in a patient who had a previous history of total knee replacement surgery. Cy. fabianii was recovered from intraoperative culture specimens identified by Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and confirmed using molecular assays. It was initially misidentified as Candida utilis by phenotypic identification. Conclusion: Due to the emergence of uncommon yeast species, it is important to accurately identify and perform antifungal susceptibility testing for uncommon yeast isolates for appropriate management.

Keywords

• cyberlindnera fabianii
• prosthetic joint infection
• invasive fungal