Biomedicines (Jan 2023)

Neurosurgical Anesthesia: Optimizing Outcomes with Agent Selection

  • Andrew Nguyen,
  • Akhil Mandavalli,
  • Michael Joseph Diaz,
  • Kevin Thomas Root,
  • Aashay Patel,
  • Jed Casauay,
  • Priyanka Perisetla,
  • Brandon Lucke-Wold

DOI
https://doi.org/10.3390/biomedicines11020372
Journal volume & issue
Vol. 11, no. 2
p. 372

Abstract

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Anesthesia in neurosurgery embodies a vital element in the development of neurosurgical intervention. This undisputed interest has offered surgeons and anesthesiologists an array of anesthetic selections to utilize, though with this allowance comes the equally essential requirement of implementing a maximally appropriate agent. To date, there remains a lack of consensus and official guidance on optimizing anesthetic choice based on operating priorities including hemodynamic parameters (e.g., CPP, ICP, MAP) in addition to the route of procedure and pathology. In this review, the authors detail the development of neuroanesthesia, summarize the advantages and drawbacks of various anesthetic classes and agents, while lastly cohesively organizing the current literature of randomized trials on neuroanesthesia across various procedures.

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