An unexpected, invasive disease of the mastoid bone and external auditory canal

Iris Krebbers; Rens M. van de Goor; Roel J.W. van Kampen; Paul H.M.H. Theunissen; Verona E. Bergshoeff

Otolaryngology Case Reports (Jun 2020)

An unexpected, invasive disease of the mastoid bone and external auditory canal

Iris Krebbers,
Rens M. van de Goor,
Roel J.W. van Kampen,
Paul H.M.H. Theunissen,
Verona E. Bergshoeff

Affiliations

Iris Krebbers: Department of Otorhinolaryngology, Head and Neck Surgery, Maastricht University Medical Center, the Netherlands; Department of Otorhinolaryngology, Head and Neck Surgery, Zuyderland Medical Center Heerlen, P.O. Box 5500, 6130, MB Sittard-Geleen, the Netherlands; Corresponding author. Department of Otorhinolaryngology, Head and Neck Surgery, Maastricht University Medical Center, the Netherlands.
Rens M. van de Goor: Department of Otorhinolaryngology, Head and Neck Surgery, Zuyderland Medical Center Heerlen, P.O. Box 5500, 6130, MB Sittard-Geleen, the Netherlands
Roel J.W. van Kampen: Department of Internal Medicine / Hematology, Zuyderland Medical Center, the Netherlands
Paul H.M.H. Theunissen: Department of Clinical Pathology, Zuyderland Medical Center, the Netherlands
Verona E. Bergshoeff: Department of Otorhinolaryngology, Head and Neck Surgery, Zuyderland Medical Center Heerlen, P.O. Box 5500, 6130, MB Sittard-Geleen, the Netherlands

Journal volume & issue: Vol. 15

Abstract

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A 65-year-old male patient with a history of Myelodysplastic Syndrome (MDS) and Systemic Mastocytosis (SM) presented with an invasive disease of the external auditory canal (EAC) and a parotid gland abscess. Abscess drainage and treatment for a malignant otitis externa (MOE) was started, which did not lead to clinical improvement. Computed Tomography (CT) of the petrous bone as well as a Positron Emission Tomography/Computed Tomography with 2-[fluorine-18]-fluoro-2-deoxy-d-glucose (FDG-PET-CT) showed bony erosion of the EAC with a symmetrical FDG distribution at the level of both EACs. Histopathological biopsies of the EAC revealed a rarely encountered localization of systemic mastocytosis (SM). Especially patients with a hematological disorder such as a MDS are at risk to develop SM. In case of a fulminant infectious disease of the EAC in these patients, a localization of SM should be considered as well. This is the first report on SM with a localization in the EAC.

Published in Otolaryngology Case Reports

ISSN: 2468-5488 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Medicine: Otorhinolaryngology
Website: https://www.journals.elsevier.com/otolaryngology-case-reports/

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