Regioselective Protection of the 4-Hydroxyl of 3,4-Dihydroxy-benzaldehyde

Abstract

The regioselective protection of the 4-hydroxyl group of 3,4-dihydroxy-benzaldehyde was accomplished with seven different protecting groups (benzyl, p-methoxybenzyl, o-nitrobenzyl, 2,6-dichlorobenzyl, 3,4-dichlorobenzyl, vinyl and propargyl) in yields ranging between 67-75%.

Keywords

• regioselective
• protection
• catechol
• 3
• 4-dihydroxybenzaldehyde Introduction