Nature Communications (May 2016)

Pre-bilaterian origin of the blastoporal axial organizer

  • Yulia Kraus,
  • Andy Aman,
  • Ulrich Technau,
  • Grigory Genikhovich

DOI
https://doi.org/10.1038/ncomms11694
Journal volume & issue
Vol. 7, no. 1
pp. 1 – 9

Abstract

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In vertebrate embryos, Wnt/β-catenin signaling induces an organizer area guiding the formation of body axes and inducing extra axes upon transplantation. Here, Kraus et al. show that Wnt ligands also induce an organizer in a sea anemone, indicating that the organizer dates back over 600 million years.