Research Progress on the Mechanism of Gastric Microecology in the Development of Gastric Cancer

Abstract

Microecology has been shown to be closely related to digestive diseases, and most of the research on gastric microecology has focused on Helicobacter pylori. With the development of microarray and gene detection technology, in addition to Helicobacter pylori, more and more bacteria genera have been discovered, such as Actinomyces, Firmicute and Clostridium. These bacteria genera and their abundance changes have also been proved to be closely related to the occurrence and development of gastric cancer. In this paper, the role and possible mechanism of gastric microecology in the occurrence and development of gastric cancer are reviewed, with the hope of providing reference for clinical diagnosis and treatment.

Keywords

• intragastric microecology
• helicobacter pylori
• gastric cancer
• mechanism of action