Brain, Behavior, & Immunity - Health (Feb 2022)

Aseptic meningitis after BNT-162b2 COVID-19 vaccination

  • Amanda CY. Chan,
  • Benjamin YQ. Tan,
  • Yihui Goh,
  • Shaun SY. Tan,
  • Paul A. Tambyah

Journal volume & issue
Vol. 19
p. 100406

Abstract

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The COVID-19 pandemic has had an unprecedented impact on healthcare systems globally, giving rise to significant morbidity and mortality. Vaccination has been widely regarded as the most important strategy to contain the pandemic. Whilst local side-effects of the BNT-162b2 (Pfizer-BioNTech) vaccine are well known, concern has emerged due to sporadic reports of immune-mediated adverse effects (Cines and Bussel, 2021; Rela et al., 2021). As of August 19, 2021, 4.54 million individuals had received COVID-19 vaccines in Singapore (Oxford Martin School UoO, 2021). We report a case series of two patients who developed aseptic meningitis after vaccination.

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