Neuropsychopharmacology Reports (Mar 2022)

Serial case report of high seizure threshold patients that responded to the lengthening of pulse width in ECT

  • Hiroshi Katagai,
  • Norio Yasui‐Furukori,
  • Hirotsugu Kawashima,
  • Taro Suwa,
  • Chieko Tsushima,
  • Yoshiteru Sato,
  • Kazutaka Shimoda,
  • Hiroichi Tasaki

DOI
https://doi.org/10.1002/npr2.12224
Journal volume & issue
Vol. 42, no. 1
pp. 105 – 108

Abstract

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Abstract Electroconvulsive therapy (ECT) has been used as an effective treatment modality for psychiatric disorders. In patients with high seizure thresholds, augmentation strategies are considered such as changing anesthetic agents, hyperventilation, and premedication with theophylline. We tried to switch to “long (1.5 ms)” brief pulse ECT in all six patients from October 2020. The successful induction of effective seizures with “long” brief pulse stimulation in five of six patients who could not be treated adequately with standard ECT. In the current situation in cases in which brief pulse ECT, with the maximum dose did not lead to effective seizures, “long” brief pulse waves may be a promising option.

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