Beilstein Journal of Organic Chemistry (Apr 2019)
Synthesis of (macro)heterocycles by consecutive/repetitive isocyanide-based multicomponent reactions
Abstract
Isocyanide-based multicomponent reactions are a versatile tool in the synthesis of heterocycles. This review describes recently developed approaches based on the combination of consecutive or repetitive isocyanide-based multicomponent reactions for the synthesis of structurally diverse heterocycles. These strategies have also allowed the synthesis of a plethora of macroheterocycles in a reduced number of steps.
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