A Study Investigating the Association of Dermatological and Infusion Reactions to Infliximab and Infliximab Trough Levels

Vivian Wai-Mei Huang; Neil Dhami; Darryl Fedorak; Connie Prosser; Carol Shalapay; Karen Ivy Kroeker; Brendan Phillip Halloran; Levinus Albert Dieleman; Richard Neil Fedorak

doi:10.1155/2015/428702

Canadian Journal of Gastroenterology and Hepatology (Jan 2015)

A Study Investigating the Association of Dermatological and Infusion Reactions to Infliximab and Infliximab Trough Levels

Vivian Wai-Mei Huang,
Neil Dhami,
Darryl Fedorak,
Connie Prosser,
Carol Shalapay,
Karen Ivy Kroeker,
Brendan Phillip Halloran,
Levinus Albert Dieleman,
Richard Neil Fedorak

Affiliations

Vivian Wai-Mei Huang: Division of Gastroenterology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
Neil Dhami: Division of Gastroenterology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
Darryl Fedorak: Division of Gastroenterology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
Connie Prosser: Division of Medical Biochemistry, Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Alberta, Canada
Carol Shalapay: Division of Medical Biochemistry, Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Alberta, Canada
Karen Ivy Kroeker: Division of Gastroenterology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
Brendan Phillip Halloran: Division of Gastroenterology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
Levinus Albert Dieleman: Division of Gastroenterology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
Richard Neil Fedorak: Division of Gastroenterology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada

DOI: https://doi.org/10.1155/2015/428702
Journal volume & issue: Vol. 29, no. 1
pp. 35 – 40

Abstract

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BACKGROUND: Although infliximab is an effective therapy for inflammatory bowel disease (IBD), it is associated with dermatological events and infusion reactions. It is not known whether a relationship between these adverse events (AEs) and infliximab trough levels (ITLs) exists.

Published in Canadian Journal of Gastroenterology and Hepatology

ISSN: 2291-2789 (Print); 2291-2797 (Online)
Publisher: Wiley
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the digestive system. Gastroenterology
Website: https://onlinelibrary.wiley.com/journal/1720

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