517 Regulatory T cell functional identity is sustained by a glucose:lactate axis that is exploited in the tumor microenvironment

• Ryan Whetstone,
• Greg Delgoffe,
• Paolo Vignali,
• Kristin DePeaux,
• McLane Watson,
• Ashley Menk,
• Steven Mullet,
• Ronal Peralta,
• Stephanie Grebinoski,
• Natalie Rittenhouse,
• Amanda Poholek,
• Brett Morrison,
• Jeffrey Rothstein,
• Stacy Wendell

Affiliations

Ryan Whetstone

Aff236 grid.21925.3d0000000419369000University of Pittsburgh Pittsburgh PA USA

Greg Delgoffe

Aff236 grid.21925.3d0000000419369000University of Pittsburgh Pittsburgh PA USA

Paolo Vignali

University of Pittsburgh SOM, Pittsburgh, Pennsylvania, USA

Kristin DePeaux

University of Pittsburgh SOM, Pittsburgh, Pennsylvania, USA

McLane Watson

University of Pittsburgh SOM, Pittsburgh, Pennsylvania, USA

Ashley Menk

University of Pittsburgh SOM, Pittsburgh, Pennsylvania, USA

Steven Mullet

1University Of Pittsburgh, Pittsburgh, PA, USA

Ronal Peralta

1University Of Pittsburgh, Pittsburgh, PA, USA

Stephanie Grebinoski

1University Of Pittsburgh, Pittsburgh, PA, USA

Natalie Rittenhouse

1University Of Pittsburgh, Pittsburgh, PA, USA

Amanda Poholek

1University Of Pittsburgh, Pittsburgh, PA, USA

Brett Morrison

2Johns Hopkins, Baltimore, MD, USA

Jeffrey Rothstein

2Johns Hopkins, Baltimore, MD, USA

Stacy Wendell

1University Of Pittsburgh, Pittsburgh, PA, USA