Intraoperative Cognitive Mapping Tasks for Direct Electrical Stimulation in Clinical and Neuroscientific Contexts

Linghao Bu; Linghao Bu; Linghao Bu; Linghao Bu; Linghao Bu; Junfeng Lu; Junfeng Lu; Junfeng Lu; Junfeng Lu; Junfeng Lu; Jie Zhang; Jie Zhang; Jie Zhang; Jie Zhang; Jie Zhang; Jinsong Wu; Jinsong Wu; Jinsong Wu; Jinsong Wu; Jinsong Wu

doi:10.3389/fnhum.2021.612891

Frontiers in Human Neuroscience (Mar 2021)

Intraoperative Cognitive Mapping Tasks for Direct Electrical Stimulation in Clinical and Neuroscientific Contexts

Linghao Bu,
Linghao Bu,
Linghao Bu,
Linghao Bu,
Linghao Bu,
Junfeng Lu,
Junfeng Lu,
Junfeng Lu,
Junfeng Lu,
Junfeng Lu,
Jie Zhang,
Jie Zhang,
Jie Zhang,
Jie Zhang,
Jie Zhang,
Jinsong Wu,
Jinsong Wu,
Jinsong Wu,
Jinsong Wu,
Jinsong Wu

Affiliations

Linghao Bu: Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China
Linghao Bu: Brain Function Laboratory, Neurosurgical Institute of Fudan University, Shanghai, China
Linghao Bu: Zhangjiang Lab, Institute of Brain-Intelligence Technology, Shanghai, China
Linghao Bu: Shanghai Key Laboratory of Brain Function and Restoration and Neural Regeneration, Shanghai, China
Linghao Bu: Shanghai Clinical Medical Center of Neurosurgery, Shanghai, China
Junfeng Lu: Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China
Junfeng Lu: Brain Function Laboratory, Neurosurgical Institute of Fudan University, Shanghai, China
Junfeng Lu: Zhangjiang Lab, Institute of Brain-Intelligence Technology, Shanghai, China
Junfeng Lu: Shanghai Key Laboratory of Brain Function and Restoration and Neural Regeneration, Shanghai, China
Junfeng Lu: Shanghai Clinical Medical Center of Neurosurgery, Shanghai, China
Jie Zhang: Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China
Jie Zhang: Brain Function Laboratory, Neurosurgical Institute of Fudan University, Shanghai, China
Jie Zhang: Zhangjiang Lab, Institute of Brain-Intelligence Technology, Shanghai, China
Jie Zhang: Shanghai Key Laboratory of Brain Function and Restoration and Neural Regeneration, Shanghai, China
Jie Zhang: Shanghai Clinical Medical Center of Neurosurgery, Shanghai, China
Jinsong Wu: Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China
Jinsong Wu: Brain Function Laboratory, Neurosurgical Institute of Fudan University, Shanghai, China
Jinsong Wu: Zhangjiang Lab, Institute of Brain-Intelligence Technology, Shanghai, China
Jinsong Wu: Shanghai Key Laboratory of Brain Function and Restoration and Neural Regeneration, Shanghai, China
Jinsong Wu: Shanghai Clinical Medical Center of Neurosurgery, Shanghai, China

DOI: https://doi.org/10.3389/fnhum.2021.612891
Journal volume & issue: Vol. 15

Abstract

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Direct electrical stimulation (DES) has been widely applied in both guidance of lesion resection and scientific research; however, the design and selection of intraoperative cognitive mapping tasks have not been updated in a very long time. We introduce updated mapping tasks for language and non-language functions and provide recommendations for optimal design and selection of intraoperative mapping tasks. In addition, with DES becoming more critical in current neuroscientific research, a task design that has not been widely used in DES yet (subtraction and conjunction paradigms) was introduced for more delicate mapping of brain functions especially for research purposes. We also illustrate the importance of designing a common task series for DES and other non-invasive mapping techniques. This review gives practical updated guidelines for advanced application of DES in clinical and neuroscientific research.

Published in Frontiers in Human Neuroscience

ISSN: 1662-5161 (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Internal medicine: Neurosciences. Biological psychiatry. Neuropsychiatry
Website: http://www.frontiersin.org/human_neuroscience

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