European Journal of Case Reports in Internal Medicine (Aug 2020)

Multi-Focal Splenic Tumour in a Belgian Patient and a Brief Review of the Literature on Littoral Cell Angioma

  • Maaike Ramael,
  • Patrick Schoeters,
  • Karl De Pooter,
  • Frederik Van Sonhoven,
  • Hilde Van Steelandt,
  • Jacqueline Swaegers,
  • Wim Develter,
  • Marc Ramael

DOI
https://doi.org/10.12890/2020_001863

Abstract

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We describe the case of a 66-year-old woman with littoral cell angioma (LCA) confirmed by histopathology and immunohistochemistry, to our knowledge the first case in Belgium. LCA is an extremely rare primary vascular tumour of the splenic red pulp, probably originating from littoral cells. If a splenic mass and nodules are incidentally identified on imaging and the patient has no associated signs or symptoms, LCA should be suspected. Histopathology and adjacent techniques are mandatory for definitive diagnosis. Splenectomy followed by adequate follow-up is necessary to exclude underlying pathology.

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