Nature Communications (Mar 2019)
Programming chain-growth copolymerization of DNA hairpin tiles for in-vitro hierarchical supramolecular organization
- Honglu Zhang,
- Yu Wang,
- Huan Zhang,
- Xiaoguo Liu,
- Antony Lee,
- Qiuling Huang,
- Fei Wang,
- Jie Chao,
- Huajie Liu,
- Jiang Li,
- Jiye Shi,
- Xiaolei Zuo,
- Lihua Wang,
- Lianhui Wang,
- Xiaoyu Cao,
- Carlos Bustamante,
- Zhongqun Tian,
- Chunhai Fan
Affiliations
- Honglu Zhang
- Division of Physical Biology and Bioimaging Center, Shanghai Synchrotron Radiation Facility, Shanghai Institute of Applied Physics, Chinese Academy of Sciences
- Yu Wang
- State Key Laboratory of Physical Chemistry of Solid Surfaces and College of Chemistry and Chemical Engineering, Xiamen University
- Huan Zhang
- Division of Physical Biology and Bioimaging Center, Shanghai Synchrotron Radiation Facility, Shanghai Institute of Applied Physics, Chinese Academy of Sciences
- Xiaoguo Liu
- School of Chemistry and Chemical Engineering, and Institute of Molecular Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University
- Antony Lee
- Department of Chemistry, Institute for Quantitative Biosciences (QB3), Department of Physics, Department of Molecular and Cell Biology, Kavli Energy Nanosciences Institute at Berkeley, Howard Hughes Medical Institute, University of California
- Qiuling Huang
- Division of Physical Biology and Bioimaging Center, Shanghai Synchrotron Radiation Facility, Shanghai Institute of Applied Physics, Chinese Academy of Sciences
- Fei Wang
- School of Chemistry and Chemical Engineering, and Institute of Molecular Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University
- Jie Chao
- Key Laboratory for Organic Electronics & Information Displays and Institute of Advanced Materials (IAM), Jiangsu National Synergistic Innovation Center for Advanced Materials (SICAM), Nanjing University of Posts and Telecommunications (NUPT)
- Huajie Liu
- Division of Physical Biology and Bioimaging Center, Shanghai Synchrotron Radiation Facility, Shanghai Institute of Applied Physics, Chinese Academy of Sciences
- Jiang Li
- Division of Physical Biology and Bioimaging Center, Shanghai Synchrotron Radiation Facility, Shanghai Institute of Applied Physics, Chinese Academy of Sciences
- Jiye Shi
- Division of Physical Biology and Bioimaging Center, Shanghai Synchrotron Radiation Facility, Shanghai Institute of Applied Physics, Chinese Academy of Sciences
- Xiaolei Zuo
- School of Chemistry and Chemical Engineering, and Institute of Molecular Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University
- Lihua Wang
- Division of Physical Biology and Bioimaging Center, Shanghai Synchrotron Radiation Facility, Shanghai Institute of Applied Physics, Chinese Academy of Sciences
- Lianhui Wang
- Key Laboratory for Organic Electronics & Information Displays and Institute of Advanced Materials (IAM), Jiangsu National Synergistic Innovation Center for Advanced Materials (SICAM), Nanjing University of Posts and Telecommunications (NUPT)
- Xiaoyu Cao
- State Key Laboratory of Physical Chemistry of Solid Surfaces and College of Chemistry and Chemical Engineering, Xiamen University
- Carlos Bustamante
- Department of Chemistry, Institute for Quantitative Biosciences (QB3), Department of Physics, Department of Molecular and Cell Biology, Kavli Energy Nanosciences Institute at Berkeley, Howard Hughes Medical Institute, University of California
- Zhongqun Tian
- State Key Laboratory of Physical Chemistry of Solid Surfaces and College of Chemistry and Chemical Engineering, Xiamen University
- Chunhai Fan
- Division of Physical Biology and Bioimaging Center, Shanghai Synchrotron Radiation Facility, Shanghai Institute of Applied Physics, Chinese Academy of Sciences
- DOI
- https://doi.org/10.1038/s41467-019-09004-4
- Journal volume & issue
-
Vol. 10,
no. 1
pp. 1 – 11
Abstract
Formation of biological filaments via intracellular supramolecular polymerization of proteins occurs under programmable and spatiotemporal control to maintain integrity. Here the authors devise a bioinspired isothermal chain-growth approach to programmably copolymerize DNA hairpin tiles into 1D nanofilaments.
