Clinical experience in the management of corneal ulcers of unknown etiology with a protracted course in presence of toxic and allergic component

Abstract

Purpose. To present a clinical case of corneal ulcer of unknown etiology in presence of patient’s acute toxic and allergic reaction in a patient who was under ophthalmological supervision for a long time, but had no positive dynamics in the treatment of the disease.Material and methods. Examination of the patient on the day of his visit suggested bacterial etiology of the process, but laboratory diagnostic tests did not reveal the etiological factor.Results. Toxic-allergic component in biomicroscopy of both eyes, long-term previous antibacterial therapy, the nature of the corneal ulcer gave rise to the appointment of therapy, the areas of which are allergy medications, antibacterial and antifungal drugs. The propriety of the prescribed treatment can be seen in the strongly positive dynamics in the course of the disease and the reduction of the ulcer defec t.Conclusion. A long course of corneal ulcer without positive dynamics is necessary in assessing the condition of patient having a toxic-allergic component. Despite the assumption about the bacterial etiology of the process, given the duration of the disease, antifungal drugs were prescribed at the beginning of therapy.

Keywords

• corneal ulcer
• toxic and allergic reaction