Considering hormone-sensitive cancers as a single disease in the UK biobank reveals shared aetiology

Muktar Ahmed; Ville-Petteri Mäkinen; Anwar Mulugeta; Jisu Shin; Terry Boyle; Elina Hyppönen; Sang Hong Lee

doi:10.1038/s42003-022-03554-y

Communications Biology (Jun 2022)

Considering hormone-sensitive cancers as a single disease in the UK biobank reveals shared aetiology

Muktar Ahmed,
Ville-Petteri Mäkinen,
Anwar Mulugeta,
Jisu Shin,
Terry Boyle,
Elina Hyppönen,
Sang Hong Lee

Affiliations

Muktar Ahmed: Australian Centre for Precision Health, University of South Australia
Ville-Petteri Mäkinen: Australian Centre for Precision Health, University of South Australia
Anwar Mulugeta: Australian Centre for Precision Health, University of South Australia
Jisu Shin: Australian Centre for Precision Health, University of South Australia
Terry Boyle: Australian Centre for Precision Health, University of South Australia
Elina Hyppönen: Australian Centre for Precision Health, University of South Australia
Sang Hong Lee: Australian Centre for Precision Health, University of South Australia

DOI: https://doi.org/10.1038/s42003-022-03554-y
Journal volume & issue: Vol. 5, no. 1
pp. 1 – 14

Abstract

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Analysis of data from the UK Biobank considering multiple hormone-sensitive cancers as a single disease suggests substantial SNP-based heritability, identifying 55 variants with genome-wide significance.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

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