NAP1-RELATED PROTEIN1 and 2 negatively regulate H2A.Z abundance in chromatin in Arabidopsis

Yafei Wang; Zhenhui Zhong; Yaxin Zhang; Linhao Xu; Suhua Feng; Shima Rayatpisheh; James A. Wohlschlegel; Zonghua Wang; Steven E. Jacobsen; Israel Ausin

doi:10.1038/s41467-020-16691-x

Nature Communications (Jun 2020)

NAP1-RELATED PROTEIN1 and 2 negatively regulate H2A.Z abundance in chromatin in Arabidopsis

Yafei Wang,
Zhenhui Zhong,
Yaxin Zhang,
Linhao Xu,
Suhua Feng,
Shima Rayatpisheh,
James A. Wohlschlegel,
Zonghua Wang,
Steven E. Jacobsen,
Israel Ausin

Affiliations

Yafei Wang: State Key Laboratory of Crop Stress Biology for Arid Areas and College of Life Sciences, Northwest A&F University
Zhenhui Zhong: Department of Molecular, Cell and Developmental Biology, University of California
Yaxin Zhang: Haixia Institute of Science and Technology, Fujian Agriculture and Forestry University
Linhao Xu: Leibniz Institute of Plant Genetics and Crop Plant Research (IPK), OT Gatersleben
Suhua Feng: Department of Molecular, Cell and Developmental Biology, University of California
Shima Rayatpisheh: Department of Biological Chemistry, David Geffen School of Medicine, University of California
James A. Wohlschlegel: Department of Biological Chemistry, David Geffen School of Medicine, University of California
Zonghua Wang: State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, College of Plant Protection, Fujian Agriculture and Forestry University
Steven E. Jacobsen: Department of Molecular, Cell and Developmental Biology, University of California
Israel Ausin: State Key Laboratory of Crop Stress Biology for Arid Areas and College of Life Sciences, Northwest A&F University

DOI: https://doi.org/10.1038/s41467-020-16691-x
Journal volume & issue: Vol. 11, no. 1
pp. 1 – 10

Abstract

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The histone variant H2A.Z is deposited by the SWR1 complex to replace H2A in Arabidopsis, but the mechanism of H2A.Z removal is unclear. Here, the authors show that NRP proteins can regulate gene expression by counteracting SWR1 and prevent excessive accumulation of H2A.Z.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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