Highly Efficient Antibacterial Polymer Composites Based on Hydrophobic Riboflavin Carbon Polymerized Dots

Zoran M. Marković; Mária Kováčová; Sanja R. Jeremić; Štefan Nagy; Dušan D. Milivojević; Pavel Kubat; Angela Kleinová; Milica D. Budimir; Marija M. Mojsin; Milena J. Stevanović; Adriana Annušová; Zdeno Špitalský; Biljana M. Todorović Marković

doi:10.3390/nano12224070

Nanomaterials (Nov 2022)

Highly Efficient Antibacterial Polymer Composites Based on Hydrophobic Riboflavin Carbon Polymerized Dots

Zoran M. Marković,
Mária Kováčová,
Sanja R. Jeremić,
Štefan Nagy,
Dušan D. Milivojević,
Pavel Kubat,
Angela Kleinová,
Milica D. Budimir,
Marija M. Mojsin,
Milena J. Stevanović,
Adriana Annušová,
Zdeno Špitalský,
Biljana M. Todorović Marković

Affiliations

Zoran M. Marković: Vinča Institute of Nuclear Sciences—National Institute of the Republic of Serbia, University of Belgrade, 11000 Belgrade, Serbia
Mária Kováčová: Polymer Institute, Slovak Academy of Sciences, Dúbravská Cestá 9, 84541 Bratislava, Slovakia
Sanja R. Jeremić: Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, Vojvode Stepe 444a, 11042 Belgrade, Serbia
Štefan Nagy: Institute of Materials and Machine Mechanics, Slovak Academy of Sciences, Dúbravská Cestá 9/6319, 84513 Bratislava, Slovakia
Dušan D. Milivojević: Vinča Institute of Nuclear Sciences—National Institute of the Republic of Serbia, University of Belgrade, 11000 Belgrade, Serbia
Pavel Kubat: J. Heyrovsky Institute of Physical Chemistry, Academy of Sciences of the Czech Republic, Dolejškova 3, 182 23 Praha, Czech Republic
Angela Kleinová: Polymer Institute, Slovak Academy of Sciences, Dúbravská Cestá 9, 84541 Bratislava, Slovakia
Milica D. Budimir: Vinča Institute of Nuclear Sciences—National Institute of the Republic of Serbia, University of Belgrade, 11000 Belgrade, Serbia
Marija M. Mojsin: Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, Vojvode Stepe 444a, 11042 Belgrade, Serbia
Milena J. Stevanović: Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, Vojvode Stepe 444a, 11042 Belgrade, Serbia
Adriana Annušová: Department of Multilayers and Nanostructures, Institute of Physics, Slovak Academy of Sciences, Dúbravská Cestá 9, 84541 Bratislava, Slovakia
Zdeno Špitalský: Polymer Institute, Slovak Academy of Sciences, Dúbravská Cestá 9, 84541 Bratislava, Slovakia
Biljana M. Todorović Marković: Vinča Institute of Nuclear Sciences—National Institute of the Republic of Serbia, University of Belgrade, 11000 Belgrade, Serbia

DOI: https://doi.org/10.3390/nano12224070
Journal volume & issue: Vol. 12, no. 22
p. 4070

Abstract

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Development of new types of antimicrobial coatings is of utmost importance due to increasing problems with pathogen transmission from various infectious surfaces to human beings. In this study, new types of highly potent antimicrobial polyurethane composite films encapsulated by hydrophobic riboflavin-based carbon polymer dots are presented. Detailed structural, optical, antimicrobial, and cytotoxic investigations of these composites were conducted. Low-power blue light triggered the composites to eradicate Escherichia coli in 30 min, whereas the same effect toward Staphylococcus aureus was reached after 60 min. These composites also show low toxicity against MRC-5 cells. In this way, RF-CPD composites can be used for sterilization of highly touched objects in the healthcare industry.

Published in Nanomaterials

ISSN: 2079-4991 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Science: Chemistry
Website: https://www.mdpi.com/journal/nanomaterials

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