Nature Communications (Oct 2022)

Sleep decreases neuronal activity control of microglial dynamics in mice

  • I. Hristovska,
  • M. Robert,
  • K. Combet,
  • J. Honnorat,
  • J-C Comte,
  • O. Pascual

DOI
https://doi.org/10.1038/s41467-022-34035-9
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 15

Abstract

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Microglia survey the parenchyma, which leads to morphology changes over time. Here the authors show using 2 photon imaging of microglia in vivo that sleep modulates microglial morphodynamics through Cx3cr1 signaling.