Crystal structure of diethyl 2-amino-5-{4-[bis(4-methylphenyl)amino]benzamido}thiophene-3,4-dicarboxylate

Abstract

In the title compound, C31H31N3O5S, the regioselective substitution of the thiophene is confirmed with the amine and the amide at the 2- and 5-positions, respectively. In the molecule, the thiophene ring is twisted by 12.82 (3)° with respect to the aromatic ring of the benzamido group. Intramolecular N—H...O hydrogen bonds are present involving the N atoms of the primary amine and the amide groups, forming S(6) ring motifs. In the crystal, centrosymmetrically related molecules are linked by pairs of N—H...O hydrogen bonds involving the amide carbonyl O atoms and the primary amine N atoms to form dimers of R22(16) ring motif.

Keywords

• crystal structure
• intra- and intermolecular bonding
• hydrogen-bonded dimer