Relationship of Plasma Osmolarity within Hospital Mortality in Patients with Acute Pulmonary Embolism

Abstract

Objective: To determine the relationship between plasma osmolarity and within-hospital mortality in patients with acute pulmonary embolism. Study Design: Cross-sectional analytical study. Place and Duration of Study: Pak-Emirates Military Hospital, Rawalpindi Pakistan, Jan 2019 to Jan 2020. Methodology: The sample population consisted of 210 patients diagnosed with pulmonary embolism and admitted to the pulmonology unit at our hospital during the study period. Patients underwent all routine investigations, including plasma osmolarity, and were followed up until discharge or death. Results: Out of 210 patients with pulmonary embolism admitted to the pulmonology unit during the study period, 194 (92.4%) were discharged as they had complete recovery, while 16(7.6%) died during their stay at the hospital despite vigorous management. After applying the inferential statistics, it was found that patients with high plasma osmolarity and low systolic blood pressure (SBP) at presentation had a significant association with in-hospital mortality among the patients suffering from pulmonary embolism. Conclusion: Pulmonary embolism emerged as a condition with considerable in-hospital mortality in our study. Increased plasma osmolarity and low systolic blood pressure (SBP) at presentation emerged as strong factors associated with increased mortality among our study participants.

Keywords

• Mortality
• Plasma osmolarity
• Pulmonary embolism