A naturally occurring mini-alanyl-tRNA synthetase

Titi Rindi Antika; Dea Jolie Chrestella; Yi-Kuan Tseng; Yi-Hung Yeh; Chwan-Deng Hsiao; Chien-Chia Wang

doi:10.1038/s42003-023-04699-0

Communications Biology (Mar 2023)

A naturally occurring mini-alanyl-tRNA synthetase

Titi Rindi Antika,
Dea Jolie Chrestella,
Yi-Kuan Tseng,
Yi-Hung Yeh,
Chwan-Deng Hsiao,
Chien-Chia Wang

Affiliations

Titi Rindi Antika: Department of Life Sciences, National Central University, Zhongli District
Dea Jolie Chrestella: Department of Life Sciences, National Central University, Zhongli District
Yi-Kuan Tseng: Graduate Institute of Statistics, National Central University, Zhongli District
Yi-Hung Yeh: Institute of Molecular Biology, Academia Sinica, Nankang District
Chwan-Deng Hsiao: Institute of Molecular Biology, Academia Sinica, Nankang District
Chien-Chia Wang: Department of Life Sciences, National Central University, Zhongli District

DOI: https://doi.org/10.1038/s42003-023-04699-0
Journal volume & issue: Vol. 6, no. 1
pp. 1 – 9

Abstract

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The mini alanyl-tRNA synthetase of the Tupanvirus, lacking the editing and C-Ala domains, can functionally substitute for its yeast counterpart in vivo and has developed a new tRNA-binding mode in absence of C-Ala.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

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