Storming the castle: A case report of multi‐system dysregulation in a child with Castleman disease

Abstract

Abstract Castleman disease is a non‐clonal, lymphoproliferative disorder rarely seen in children. Presented is a 12‐year‐old male with progressive abdominal pain, vomiting, and fever. Diagnostic testing revealed multi‐organ system involvement and the diagnosis was ultimately made with tissue biopsy. Marked disease regression occurred after high‐dose steroids and continued interleukin‐6 inhibition.

Keywords

• angiofollicular
• Castleman
• hyperplasia
• interleukin‐6
• lymphoproliferative