Communications Biology (Oct 2021)
Features of repertoire diversity and gene expression in human cytotoxic T cells following allogeneic hematopoietic cell transplantation
- Hideki Nakasone,
- Machiko Kusuda,
- Kiriko Terasako-Saito,
- Koji Kawamura,
- Yu Akahoshi,
- Masakatsu Kawamura,
- Junko Takeshita,
- Shunto Kawamura,
- Nozomu Yoshino,
- Kazuki Yoshimura,
- Yukiko Misaki,
- Ayumi Gomyo,
- Kazuaki Kameda,
- Masaharu Tamaki,
- Aki Tanihara,
- Shun-ichi Kimura,
- Shinichi Kako,
- Yoshinobu Kanda
Affiliations
- Hideki Nakasone
- Division of Hematology, Jichi Medical University Saitama Medical Center
- Machiko Kusuda
- Division of Hematology, Jichi Medical University Saitama Medical Center
- Kiriko Terasako-Saito
- Division of Hematology, Jichi Medical University Saitama Medical Center
- Koji Kawamura
- Division of Hematology, Jichi Medical University Saitama Medical Center
- Yu Akahoshi
- Division of Hematology, Jichi Medical University Saitama Medical Center
- Masakatsu Kawamura
- Division of Hematology, Jichi Medical University Saitama Medical Center
- Junko Takeshita
- Division of Hematology, Jichi Medical University Saitama Medical Center
- Shunto Kawamura
- Division of Hematology, Jichi Medical University Saitama Medical Center
- Nozomu Yoshino
- Division of Hematology, Jichi Medical University Saitama Medical Center
- Kazuki Yoshimura
- Division of Hematology, Jichi Medical University Saitama Medical Center
- Yukiko Misaki
- Division of Hematology, Jichi Medical University Saitama Medical Center
- Ayumi Gomyo
- Division of Hematology, Jichi Medical University Saitama Medical Center
- Kazuaki Kameda
- Division of Hematology, Jichi Medical University Saitama Medical Center
- Masaharu Tamaki
- Division of Hematology, Jichi Medical University Saitama Medical Center
- Aki Tanihara
- Division of Hematology, Jichi Medical University Saitama Medical Center
- Shun-ichi Kimura
- Division of Hematology, Jichi Medical University Saitama Medical Center
- Shinichi Kako
- Division of Hematology, Jichi Medical University Saitama Medical Center
- Yoshinobu Kanda
- Division of Hematology, Jichi Medical University Saitama Medical Center
- DOI
- https://doi.org/10.1038/s42003-021-02709-7
- Journal volume & issue
-
Vol. 4,
no. 1
pp. 1 – 18
Abstract
Cytomegalovirus reactivation is an important concern after allogeneic stem cell transplantation (allo-HCT) or organ transplantation. Here, Hideki Nakasone et al. investigate changes in repertoire diversity and gene expression among clinically-transferred T cells to improve our understanding of immune reconstitution following allo-HCT.