Data on differentially expressed miRNAs in dogs infected with Leishmania infantum

Jaqueline Poleto Bragato; Larissa Martins Melo; Gabriela Lovizutto Venturin; Gabriela Torres Rebech; Leandro Encarnação Garcia; Flavia Lombardi Lopes; Valéria Marçal Felix de Lima

Data in Brief (Apr 2018)

Data on differentially expressed miRNAs in dogs infected with Leishmania infantum

Jaqueline Poleto Bragato,
Larissa Martins Melo,
Gabriela Lovizutto Venturin,
Gabriela Torres Rebech,
Leandro Encarnação Garcia,
Flavia Lombardi Lopes,
Valéria Marçal Felix de Lima

Affiliations

Jaqueline Poleto Bragato: Department of Animal Clinic, Surgery and Reproduction, São Paulo State University (Unesp), School of Veterinary Medicine, Araçatuba, São Paulo, Brazil
Larissa Martins Melo: Department of Animal Clinic, Surgery and Reproduction, São Paulo State University (Unesp), School of Veterinary Medicine, Araçatuba, São Paulo, Brazil
Gabriela Lovizutto Venturin: Department of Animal Clinic, Surgery and Reproduction, São Paulo State University (Unesp), School of Veterinary Medicine, Araçatuba, São Paulo, Brazil
Gabriela Torres Rebech: Department of Animal Clinic, Surgery and Reproduction, São Paulo State University (Unesp), School of Veterinary Medicine, Araçatuba, São Paulo, Brazil
Leandro Encarnação Garcia: Department of Support, Production and Animal Health, São Paulo State University (Unesp), School of Veterinary Medicine, Araçatuba, São Paulo, Brazil
Flavia Lombardi Lopes: Department of Support, Production and Animal Health, São Paulo State University (Unesp), School of Veterinary Medicine, Araçatuba, São Paulo, Brazil
Valéria Marçal Felix de Lima: Department of Animal Clinic, Surgery and Reproduction, São Paulo State University (Unesp), School of Veterinary Medicine, Araçatuba, São Paulo, Brazil; Correspondence to: St. Clóvis Pestana, 793 Ipanema, Araçatuba, SP 16050-680, Brazil.

Journal volume & issue: Vol. 17
pp. 218 – 225

Abstract

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This paper contains data on differentially expressed miRNAs in peripheral blood mononuclear cells (PBMC) of dogs naturally infected by Leishmania (L.) infantum compared to healthy dogs. In recent years, studies with miRNAs have shown that these molecules play a critical role in the regulation and function of immune response.Differentially expressed miRNAs were identified by microarray, validated by real time PCR and compared with parasite load in the dogs. Targets and pathways were analyzed using the Ingenuity Pathway Analysis program. Keywords: Dog, Leishmania infantum, miRNA

Published in Data in Brief

ISSN: 2352-3409 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Computer applications to medicine. Medical informatics; Science: Science (General)
Website: http://www.journals.elsevier.com/data-in-brief/

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