Glycan shield of the ebolavirus envelope glycoprotein GP

Weiwei Peng; Vamseedhar Rayaprolu; Amar D. Parvate; Matti F. Pronker; Sean Hui; Diptiben Parekh; Kelly Shaffer; Xiaoying Yu; Erica O. Saphire; Joost Snijder

doi:10.1038/s42003-022-03767-1

Communications Biology (Aug 2022)

Glycan shield of the ebolavirus envelope glycoprotein GP

Weiwei Peng,
Vamseedhar Rayaprolu,
Amar D. Parvate,
Matti F. Pronker,
Sean Hui,
Diptiben Parekh,
Kelly Shaffer,
Xiaoying Yu,
Erica O. Saphire,
Joost Snijder

Affiliations

Weiwei Peng: Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute of Pharmaceutical Sciences, Utrecht University
Vamseedhar Rayaprolu: Center for Infectious Disease and Vaccine Discovery, La Jolla Institute for Immunology
Amar D. Parvate: Center for Infectious Disease and Vaccine Discovery, La Jolla Institute for Immunology
Matti F. Pronker: Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute of Pharmaceutical Sciences, Utrecht University
Sean Hui: Center for Infectious Disease and Vaccine Discovery, La Jolla Institute for Immunology
Diptiben Parekh: Center for Infectious Disease and Vaccine Discovery, La Jolla Institute for Immunology
Kelly Shaffer: Center for Infectious Disease and Vaccine Discovery, La Jolla Institute for Immunology
Xiaoying Yu: Center for Infectious Disease and Vaccine Discovery, La Jolla Institute for Immunology
Erica O. Saphire: Center for Infectious Disease and Vaccine Discovery, La Jolla Institute for Immunology
Joost Snijder: Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute of Pharmaceutical Sciences, Utrecht University

DOI: https://doi.org/10.1038/s42003-022-03767-1
Journal volume & issue: Vol. 5, no. 1
pp. 1 – 11

Abstract

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Site-specific N-, O-, and C-linked glycans are characterized in the ebolavirus envelope glycoprotein GP using mass spectrometry-based glycoproteomics.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

About the journal