Nature Communications (Dec 2017)
A modular synthesis of tetracyclic meroterpenoid antibiotics
Abstract
Polycyclic meroterpenoids show a wide range of biological activities. Here, the authors report a modular approach to synthesize a number of natural and non-natural tetracyclic meroterpenoids, which display antibiotic activity against methicillin-resistant Staphylococcus aureus.